Hypertension matters.

Hypertension is prevalent worldwide. Despite continual efforts to improve its management, blood pressure control rates have declined substantially over the past two decades. Untreated, hypertension can lead to many significant health problems — and many people don’t even realize they have it.

1.28 billion adults
worldwide have hypertension.*

*World Health Organization; https://www.who.int/news-room/fact-sheets/detail/hypertension; accessed on 7/09/2023

A significant number of treated hypertension patients have resistant and/or uncontrolled hypertension1

  1. Zhang et al. Hypertension. 2017 Oct;70(4):736-742. Online Supplement – 2013-14 Data.
  2. Carey et al. Hypertension. 2019 Feb;73(2):424-431.

Left undetected or untreated over time, hypertension can lead to:

• Ischemic heart disease, including myocardial infarction
• Stroke
• Heart failure
• Chronic renal failure
• Cognitive decline



Hypertension is associated with five years reduced life expectancy.1

1. Stroke and High Blood pressure correlation – AHA – High Blood Pressure and Stroke Infographic | American Stroke Association

Patients with resistant hypertension are at risk of heart disease and stroke — two of the leading causes of death worldwide.


of heart attacks and strokes are associated with high blood pressure1

1. Lawes et al. Lancet. 2008 May 3;371(9623):1513-8

A 10 mmHg drop in
office systolic blood
pressure reduces
risk by:1

Meta-analysis of 613,815 patients

from 123 studies.


Heart failure




CV events*


Coronary disease




Chronic renal failure

*Defined as fatal and non-fatal myocardial infarction, sudden cardiac death, re-vascularization, fatal and non-fatal stroke, and fatal and non-fatal heart failure

  1. Ettehad et al. Lancet 2016; 387: 957–67

When medication isn’t enough.

Nonadherence increases with increasing drug prescriptions1

Patients with resistant hypertension struggle to reduce blood pressure due to poor adherence to medication, side effects, and lack of response to medications.

Take on hypertension with a new tool in your arsenal.

Ultrasound renal denervation (RDN) can be used as part of a multi-modal approach to treat patients resistant to hypertension.

Discover the Paradise® Ultrasound Renal Denervation (RDN) system — the first-ever minimally invasive procedure to treat hypertension with ultrasound.