
1.28 billion adults worldwide have hypertension.*
*World Health Organization; https://www.who.int/news-room/fact-sheets/detail/hypertension accessed on 7/09/2023
Know the numbers.
A significant number of treated hypertension patients have resistant and/or uncontrolled hypertension.1
The Paradise Ultrasound Renal Denervation (uRDN) Procedure is a proven therapy option to lower your patients’ blood pressure.
Hypertension Patients in the U.S.

>100 Million
Patients with hypertension recommended for treatment (lifestyle changes and medication)1

45 Million
Uncontrolled hypertension with blood pressure > 140/901

5.5 Million
Resistant hypertension with blood pressure > 140/90 and on +3 medications1
- Based on population factors from NHANES 2017-2020. Center for Disease Control and Prevention (CDC). May 12, 2023. Numbers adjusted to account for 2025 U.S.A. population estimates.
Understanding the risks.

5 years
Hypertension is associated with five years reduced life expectancy.1
50%
Half of heart attacks and strokes are associated with high blood pressure.2
If left undetected or untreated over time, hypertension can lead to:
- Ischemic heart disease, including myocardial infarction
- Stroke
- Heart failure
- Chronic renal failure
- Cognitive decline
- Stroke and High Blood pressure correlation – AHA – High Blood Pressure and Stroke Infographic | American Stroke Association
- Lawes et al. Lancet. 2008 May 3;371(9623):1513-8
Improve outcomes.
A 10 mmHg drop in office systolic blood pressure reduces risk by1:
Meta-analysis of 613,815 patients from 123 studies.

-28%
Heart failure

-27%
Stroke

-20%
CV events*

-17%
Coronary disease

-13%
Mortality

-5%
Chronic renal failure
See how The Paradise Ultrasound Renal Denervation System can help achieve these outcomes.
- Ettehad et al. Lancet 2016; 387: 957–67
*Defined as fatal and non-fatal myocardial infarction, sudden cardiac death, re-vascularization,
fatal and non-fatal stroke, and fatal and non-fatal heart failure
When medication is not enough.
Nonadherence increases with increasing drug prescriptions.1
Patients with resistant hypertension struggle to reduce blood pressure due to poor adherence to medication, side effects, and lack of response to medication.

- Gupta et al. Hypertension 2017;69:1113-1120.
Discover the Paradise® Ultrasound Renal Denervation (uRDN) system — the first-ever minimally invasive procedure to treat hypertension with ultrasound.

Take on hypertension with a new tool in your arsenal.

Ultrasound Renal Denervation (uRDN) can be used as part of a multi-modal approach to treat patients resistant to hypertension.


“Ultrasound renal denervation can deliver meaningful and sustained blood pressure reductions even in real-world settings—without increasing medication burden. It’s a powerful validation of the therapy’s potential and a promising step toward broader adoption in the management of hypertension.”
— Dr. Michael J. Bloch
University of Nevada School of Medicine & Renown Institute of Heart and Vascular Health, NV

